Inst. of Health & Biomedical Innovation
Kelvin Grove Campus
Brisbane QLD Australia 4059
Biographical Sketch: Ken Beagley is a Professor of Immunology and Deputy Director at the Institute of Health and Biomedical Innovation at Queensland University of Technology. He has worked in the area of mucosal immunology for the past 25 years at the University of Alabama at Birmingham and the University of Newcastle prior to moving to QUT. Current research interests focus on immunity to sexually transmitted infections, in particular Chlamydia trachomatis. The aim of these studies is to define and differentiate the immune parameters of immune-mediated inflammatory pathology caused by Chlamydia infection from the immune mechanisms that can protect against chlamydial infection and to use this information to develop effective chlamydial vaccines. This work involves the use of both mouse and guinea pig models of chlamydial infection and has recently been extended to include development of a chlamydial vaccine for the koala. In all of these studies novel needle-free vaccination routes such as intranasal, sublingual and transcutaneous immunization, which target immunity to the female and male reproductive tracts are being evaluated alongside conventional injectable methods of immunization. Other research interests include the effects of chlamydial infections on spermatogenesis and ovarian function, the development of novel topical microbicide/spermicide dual action therapeutics and modulation of innate and adaptive immunity by sex hormones.
Any personal financial relationships? No
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Opening Keynote Lecture
Presidential Session
ICMI Awards, Keynote Lectures
Inflammation or Protection: The Role of IL-17 in Chlamydial Infection
F.69 Male IgG Seroconversion to Urogenital Chlamydial Infection Exacerbates Immunopathology in Females
F.119 Oral immunization induces an effective mucosal immune response that protects mice against intravaginal HSV-2 challenge